Global Protein Degradation Therapy Market Report, History and Forecast 2018-2034, Breakdown Data by Companies, Key Regions, Types and Application

Published on: 2024-01-04 | No of Pages : 400 | Industry : Medical

Publisher : MRA | Format : PDF

Global Protein Degradation Therapy Market Report, History and Forecast 2018-2034, Breakdown Data by Companies, Key Regions, Types and Application

Targeted protein degradation (TPD) has surfaced as a novel and innovative chemical tool and therapeutic modality. By co-opting protein degradation pathways, TPD facilitates complete removal of the protein molecules from within or outside the cell. While the pioneering Proteolysis-Targeting Chimera (PROTAC) technology and molecular glues hijack the ubiquitin-proteasome system, newer modalities co-opt autophagy or the endo-lysosomal pathway.
Protein Degradation Therapy report published by MRAResearch reveals that COVID-19 and Russia-Ukraine War impacted the market dually in 2022. Global Protein Degradation Therapy market is projected to reach US$ 1821.4 million in 2033, increasing from US$ 1132 million in 2022, with the CAGR of 6.3% during the period of 2023 to 2033. Demand from Cancer and Neuroscience are the major drivers for the industry.
The Protein Degradation Therapy market has gained momentum as a promising approach in drug development. This innovative strategy aims to target disease-causing proteins by facilitating their degradation within cells. Proteins that contribute to diseases like cancer and neurodegenerative disorders can be selectively broken down using small molecules known as proteolysis-targeting chimeras (PROTACs) or other protein degraders. This approach offers advantages over traditional inhibition methods, potentially leading to more effective treatments with reduced side effects. As researchers delve into protein-protein interactions and cellular mechanisms, the Protein Degradation Therapy market is expanding, presenting opportunities to address previously challenging diseases and advance precision medicine. Clinical progress and continued research in this field are expected to shape the future of therapeutic interventions.
Report Scope
This report, based on historical analysis (2018-2022) and forecast calculation (2023-2033), aims to help readers to get a comprehensive understanding of global Protein Degradation Therapy market with multiple angles, which provides sufficient supports to readers’ strategy and decision making.
Companies, Type, Application and Regions Listed in the Report

By Company

Arvinas
Nurix Therapeutics
Kymera Therapeutics
C4 Therapeutics
Segment by Type
ARV-110
ARV-471
Other

Segment by Application

Cancer
Neuroscience
Other
By Region
North America
United States
Canada
Europe
Germany
France
U.K.
Italy
Russia
Nordic Countries

Asia-Pacific
China
Japan
South Korea
Southeast Asia
India
Australia

Latin America
Mexico
Brazil

Middle East & Africa
Turkey
Saudi Arabia
UAE
Each chapter of the report provides detailed information for readers to understand the Protein Degradation Therapy market further
Chapter 1Global and regional market size and CAGR for the history and forecast period (2018-2023, 2024-2033).
Chapter 2Product Types and Revenue analysis of Each Type in North America, Europe, Asia-Pacific, Latin America, Middle East and Africa from 2018 to 2023.
Chapter 3Product Application and Revenue analysis of Each Application in North America, Europe, Asia-Pacific, Latin America, Middle East and Africa from 2018 to 2023.
Chapter 4Company Competition Status, Detailed analysis of Product Name companies’ competitive landscape, revenue, market share and ranking, latest development plan, merger, and acquisition information, etc.
Chapter 5Companies’ Outline, covering company’s basic information, Protein Degradation Therapy introduction, etc. Protein Degradation Therapy Revenue and Gross Margin of each company as well as Recent Development are also contained in this part.
Chapter 6 to 10Country Level analysis of North America, Europe, Asia-Pacific, Latin America, Middle East and Africa by revenue.
Chapter 11Market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by companies in the industry.
Chapter 12MRAResearch’s Conclusions of Protein Degradation Therapy market based on comprehensive survey.
Chapter 13Methodology and Data Sources adopted by MRAResearch.

Table of Content

1 Market Overview of Protein Degradation Therapy
1.1 Protein Degradation Therapy Market Overview
1.1.1 Protein Degradation Therapy Product Scope
1.1.2 Protein Degradation Therapy Market Status and Outlook
1.2 Global Protein Degradation Therapy Market Size Overview by Region 2018 VS 2022 VS 2033
1.3 Global Protein Degradation Therapy Market Size by Region (2018-2033)
1.4 Global Protein Degradation Therapy Historic Market Size by Region (2018-2023)
1.5 Global Protein Degradation Therapy Market Size Forecast by Region (2024-2033)
1.6 Key Regions, Protein Degradation Therapy Market Size (2018-2033)
1.6.1 North America Protein Degradation Therapy Market Size (2018-2033)
1.6.2 Europe Protein Degradation Therapy Market Size (2018-2033)
1.6.3 Asia-Pacific Protein Degradation Therapy Market Size (2018-2033)
1.6.4 Latin America Protein Degradation Therapy Market Size (2018-2033)
1.6.5 Middle East & Africa Protein Degradation Therapy Market Size (2018-2033)
2 Protein Degradation Therapy Market by Type
2.1 Introduction
2.1.1 ARV-110
2.1.2 ARV-471
2.1.3 Other
2.2 Global Protein Degradation Therapy Market Size by Type: 2018 VS 2022 VS 2033
2.2.1 Global Protein Degradation Therapy Historic Market Size by Type (2018-2023)
2.2.2 Global Protein Degradation Therapy Forecasted Market Size by Type (2024-2033)
2.3 Key Regions Market Size by Type
2.3.1 North America Protein Degradation Therapy Revenue Breakdown by Type (2018-2033)
2.3.2 Europe Protein Degradation Therapy Revenue Breakdown by Type (2018-2033)
2.3.3 Asia-Pacific Protein Degradation Therapy Revenue Breakdown by Type (2018-2033)
2.3.4 Latin America Protein Degradation Therapy Revenue Breakdown by Type (2018-2033)
2.3.5 Middle East and Africa Protein Degradation Therapy Revenue Breakdown by Type (2018-2033)
3 Protein Degradation Therapy Market Overview by Application
3.1 Introduction
3.1.1 Cancer
3.1.2 Neuroscience
3.1.3 Other
3.2 Global Protein Degradation Therapy Market Size by Application: 2018 VS 2022 VS 2033
3.2.1 Global Protein Degradation Therapy Historic Market Size by Application (2018-2023)
3.2.2 Global Protein Degradation Therapy Forecasted Market Size by Application (2024-2033)
3.3 Key Regions Market Size by Application
3.3.1 North America Protein Degradation Therapy Revenue Breakdown by Application (2018-2033)
3.3.2 Europe Protein Degradation Therapy Revenue Breakdown by Application (2018-2033)
3.3.3 Asia-Pacific Protein Degradation Therapy Revenue Breakdown by Application (2018-2033)
3.3.4 Latin America Protein Degradation Therapy Revenue Breakdown by Application (2018-2033)
3.3.5 Middle East and Africa Protein Degradation Therapy Revenue Breakdown by Application (2018-2033)
4 Protein Degradation Therapy Competition Analysis by Players
4.1 Global Protein Degradation Therapy Market Size by Players (2018-2023)
4.2 Global Top Players by Company Type (Tier 1, Tier 2 and Tier 3) & (based on the Revenue in Protein Degradation Therapy as of 2022)
4.3 Date of Key Players Enter into Protein Degradation Therapy Market
4.4 Global Top Players Protein Degradation Therapy Headquarters and Area Served
4.5 Key Players Protein Degradation Therapy Product Solution and Service
4.6 Competitive Status
4.6.1 Protein Degradation Therapy Market Concentration Rate
4.6.2 Mergers & Acquisitions, Expansion Plans
5 Company (Top Players) Profiles
5.1 Arvinas
5.1.1 Arvinas Profile
5.1.2 Arvinas Main Business
5.1.3 Arvinas Protein Degradation Therapy Products, Services and Solutions
5.1.4 Arvinas Protein Degradation Therapy Revenue (US$ Million) & (2018-2023)
5.1.5 Arvinas Recent Developments
5.2 Nurix Therapeutics
5.2.1 Nurix Therapeutics Profile
5.2.2 Nurix Therapeutics Main Business
5.2.3 Nurix Therapeutics Protein Degradation Therapy Products, Services and Solutions
5.2.4 Nurix Therapeutics Protein Degradation Therapy Revenue (US$ Million) & (2018-2023)
5.2.5 Nurix Therapeutics Recent Developments
5.3 Kymera Therapeutics
5.3.1 Kymera Therapeutics Profile
5.3.2 Kymera Therapeutics Main Business
5.3.3 Kymera Therapeutics Protein Degradation Therapy Products, Services and Solutions
5.3.4 Kymera Therapeutics Protein Degradation Therapy Revenue (US$ Million) & (2018-2023)
5.3.5 C4 Therapeutics Recent Developments
5.4 C4 Therapeutics
5.4.1 C4 Therapeutics Profile
5.4.2 C4 Therapeutics Main Business
5.4.3 C4 Therapeutics Protein Degradation Therapy Products, Services and Solutions
5.4.4 C4 Therapeutics Protein Degradation Therapy Revenue (US$ Million) & (2018-2023)
5.4.5 C4 Therapeutics Recent Developments
6 North America
6.1 North America Protein Degradation Therapy Market Size by Country (2018-2033)
6.2 United States
6.3 Canada
7 Europe
7.1 Europe Protein Degradation Therapy Market Size by Country (2018-2033)
7.2 Germany
7.3 France
7.4 U.K.
7.5 Italy
7.6 Russia
7.7 Nordic Countries
7.8 Rest of Europe
8 Asia-Pacific
8.1 Asia-Pacific Protein Degradation Therapy Market Size by Region (2018-2033)
8.2 China
8.3 Japan
8.4 South Korea
8.5 Southeast Asia
8.6 India
8.7 Australia
8.8 Rest of Asia-Pacific
9 Latin America
9.1 Latin America Protein Degradation Therapy Market Size by Country (2018-2033)
9.2 Mexico
9.3 Brazil
9.4 Rest of Latin America
10 Middle East & Africa
10.1 Middle East & Africa Protein Degradation Therapy Market Size by Country (2018-2033)
10.2 Turkey
10.3 Saudi Arabia
10.4 UAE
10.5 Rest of Middle East & Africa
11 Protein Degradation Therapy Market Dynamics
11.1 Protein Degradation Therapy Industry Trends
11.2 Protein Degradation Therapy Market Drivers
11.3 Protein Degradation Therapy Market Challenges
11.4 Protein Degradation Therapy Market Restraints
12 Research Finding /Conclusion
13 Methodology and Data Source
13.1 Methodology/Research Approach
13.1.1 Research Programs/Design
13.1.2 Market Size Estimation
13.1.3 Market Breakdown and Data Triangulation
13.2 Data Source
13.2.1 Secondary Sources
13.2.2 Primary Sources
13.3 Disclaimer
13.4 Author List

List of Figure

List of Tables
Table 1. Global Market Protein Degradation Therapy Market Size (US$ Million) Comparison by Region 2018 VS 2022 VS 2033
Table 2. Global Protein Degradation Therapy Market Size by Region (2018-2023) & (US$ Million)
Table 3. Global Protein Degradation Therapy Market Size Share by Region (2018-2023)
Table 4. Global Protein Degradation Therapy Forecasted Market Size by Region (2024-2033) & (US$ Million)
Table 5. Global Protein Degradation Therapy Forecasted Market Size Share by Region (2024-2033)
Table 6. Global Protein Degradation Therapy Market Size (US$ Million) by Type: 2018 VS 2022 VS 2033
Table 7. Global Protein Degradation Therapy Market Size by Type (2018-2023) & (US$ Million)
Table 8. Global Protein Degradation Therapy Revenue Market Share by Type (2018-2023)
Table 9. Global Protein Degradation Therapy Forecasted Market Size by Type (2024-2033) & (US$ Million)
Table 10. Global Protein Degradation Therapy Revenue Market Share by Type (2024-2033)
Table 11. North America Protein Degradation Therapy Revenue by Type (2018-2023) & (US$ Million)
Table 12. North America Protein Degradation Therapy Revenue by Type (2024-2033) & (US$ Million)
Table 13. Europe Protein Degradation Therapy Revenue by Type (2018-2023) & (US$ Million)
Table 14. Europe Protein Degradation Therapy Revenue by Type (2024-2033) & (US$ Million)
Table 15. Asia-Pacific Protein Degradation Therapy Revenue by Type (2018-2023) & (US$ Million)
Table 16. Asia-Pacific Protein Degradation Therapy Revenue by Type (2024-2033) & (US$ Million)
Table 17. Latin America Protein Degradation Therapy Revenue by Type (2018-2023) & (US$ Million)
Table 18. Latin America Protein Degradation Therapy Revenue by Type (2024-2033) & (US$ Million)
Table 19. Middle East and Africa Protein Degradation Therapy Revenue by Type (2018-2023) & (US$ Million)
Table 20. Middle East and Africa Protein Degradation Therapy Revenue by Type (2024-2033) & (US$ Million)
Table 21. Global Protein Degradation Therapy Market Size (US$ Million) by Application: 2018 VS 2022 VS 2033
Table 22. Global Protein Degradation Therapy Market Size by Application (2018-2023) & (US$ Million)
Table 23. Global Protein Degradation Therapy Revenue Market Share by Application (2018-2023)
Table 24. Global Protein Degradation Therapy Forecasted Market Size by Application (2024-2033) & (US$ Million)
Table 25. Global Protein Degradation Therapy Revenue Market Share by Application (2024-2033)
Table 26. North America Protein Degradation Therapy Revenue by Application (2018-2023) & (US$ Million)
Table 27. North America Protein Degradation Therapy Revenue by Application (2024-2033) & (US$ Million)
Table 28. Europe Protein Degradation Therapy Revenue by Application (2018-2023) & (US$ Million)
Table 29. Europe Protein Degradation Therapy Revenue by Application (2024-2033) & (US$ Million)
Table 30. Asia-Pacific Protein Degradation Therapy Revenue by Application (2018-2023) & (US$ Million)
Table 31. Asia-Pacific Protein Degradation Therapy Revenue by Application (2024-2033) & (US$ Million)
Table 32. Latin America Protein Degradation Therapy Revenue by Application (2018-2023) & (US$ Million)
Table 33. Latin America Protein Degradation Therapy Revenue by Application (2024-2033) & (US$ Million)
Table 34. Middle East and Africa Protein Degradation Therapy Revenue by Application (2018-2023) & (US$ Million)
Table 35. Middle East and Africa Protein Degradation Therapy Revenue by Application (2024-2033) & (US$ Million)
Table 36. Global Protein Degradation Therapy Revenue (US$ Million) by Players (2018-2023)
Table 37. Global Protein Degradation Therapy Revenue Market Share by Players (2018-2023)
Table 38. Global Top Players Market Share by Company Type (Tier 1, Tier 2 and Tier 3) & (based on the Revenue in Protein Degradation Therapy as of 2022)
Table 39. Date of Key Players Enter into Protein Degradation Therapy Market
Table 40. Global Protein Degradation Therapy Key Players Headquarters and Area Served
Table 41. Protein Degradation Therapy Product Solution and Service
Table 42. Global Protein Degradation Therapy Players Market Concentration Ratio (CR5 and HHI)
Table 43. Mergers & Acquisitions, Expansion Plans
Table 44. Arvinas Basic Information List
Table 45. Arvinas Description and Business Overview
Table 46. Arvinas Protein Degradation Therapy Products, Services and Solutions
Table 47. Revenue (US$ Million) in Protein Degradation Therapy Business of Arvinas (2018-2023)
Table 48. Arvinas Recent Developments
Table 49. Nurix Therapeutics Basic Information List
Table 50. Nurix Therapeutics Description and Business Overview
Table 51. Nurix Therapeutics Protein Degradation Therapy Products, Services and Solutions
Table 52. Revenue (US$ Million) in Protein Degradation Therapy Business of Nurix Therapeutics (2018-2023)
Table 53. Nurix Therapeutics Recent Developments
Table 54. Kymera Therapeutics Basic Information List
Table 55. Kymera Therapeutics Description and Business Overview
Table 56. Kymera Therapeutics Protein Degradation Therapy Products, Services and Solutions
Table 57. Revenue (US$ Million) in Protein Degradation Therapy Business of Kymera Therapeutics (2018-2023)
Table 58. Kymera Therapeutics Recent Developments
Table 59. C4 Therapeutics Basic Information List
Table 60. C4 Therapeutics Description and Business Overview
Table 61. C4 Therapeutics Protein Degradation Therapy Products, Services and Solutions
Table 62. Revenue (US$ Million) in Protein Degradation Therapy Business of C4 Therapeutics (2018-2023)
Table 63. C4 Therapeutics Recent Developments
Table 64. North America Protein Degradation Therapy Market Size by Country (2018-2023) & (US$ Million)
Table 65. North America Protein Degradation Therapy Market Size by Country (2024-2033) & (US$ Million)
Table 66. Europe Protein Degradation Therapy Market Size by Country (2018-2023) & (US$ Million)
Table 67. Europe Protein Degradation Therapy Market Size by Country (2024-2033) & (US$ Million)
Table 68. Asia-Pacific Protein Degradation Therapy Market Size Growth Rate (CAGR) by Region (US$ Million): 2018 VS 2022 VS 2033
Table 69. Asia-Pacific Protein Degradation Therapy Market Size by Region (2018-2023) & (US$ Million)
Table 70. Asia-Pacific Protein Degradation Therapy Market Size by Region (2024-2033) & (US$ Million)
Table 71. Asia-Pacific Protein Degradation Therapy Market Share by Region (2018-2023)
Table 72. Asia-Pacific Protein Degradation Therapy Market Share by Region (2024-2033)
Table 73. Latin America Protein Degradation Therapy Market Size Growth Rate (CAGR) by Region (US$ Million): 2018 VS 2022 VS 2033
Table 74. Latin America Protein Degradation Therapy Market Size by Country (2018-2023) & (US$ Million)
Table 75. Latin America Protein Degradation Therapy Market Size by Country (2024-2033) & (US$ Million)
Table 76. Middle East & Africa Protein Degradation Therapy Market Size Growth Rate (CAGR) by Region (US$ Million): 2018 VS 2022 VS 2033
Table 77. Middle East & Africa Protein Degradation Therapy Market Size by Country (2018-2023) & (US$ Million)
Table 78. Middle East & Africa Protein Degradation Therapy Market Size by Country (2024-2033) & (US$ Million)
Table 79. Protein Degradation Therapy Market Trends
Table 80. Protein Degradation Therapy Market Drivers
Table 81. Protein Degradation Therapy Market Challenges
Table 82. Protein Degradation Therapy Market Restraints
Table 83. Research Programs/Design for This Report
Table 84. Key Data Information from Secondary Sources
Table 85. Key Data Information from Primary Sources
List of Figures
Figure 1. Global Protein Degradation Therapy Market Size Year-over-Year 2018-2033 & (US$ Million)
Figure 2. Global Protein Degradation Therapy Market Size (US$ Million), 2018 VS 2022 VS 2033
Figure 3. Global Protein Degradation Therapy Market Share by Regions: 2022 VS 2033
Figure 4. Global Protein Degradation Therapy Forecasted Market Size Share by Region (2024-2033)
Figure 5. North America Protein Degradation Therapy Market Size Growth Rate (2018-2033) & (US$ Million)
Figure 6. Europe Protein Degradation Therapy Market Size Growth Rate (2018-2033) & (US$ Million)
Figure 7. Asia-Pacific Protein Degradation Therapy Market Size Growth Rate (2018-2033) & (US$ Million)
Figure 8. Latin America Protein Degradation Therapy Market Size Growth Rate (2018-2033) & (US$ Million)
Figure 9. Middle East & Africa Protein Degradation Therapy Market Size Growth Rate (2018-2033) & (US$ Million)
Figure 10. Product Picture of ARV-110
Figure 11. Global ARV-110 Market Size (US$ Million) & YoY Growth (2018-2033)
Figure 12. Product Picture of ARV-471
Figure 13. Global ARV-471 Market Size (US$ Million) & YoY Growth (2018-2033)
Figure 14. Product Picture of Other
Figure 15. Global Other Market Size (US$ Million) & YoY Growth (2018-2033)
Figure 16. Global Protein Degradation Therapy Market Size Share by Type: 2022 & 2033
Figure 17. North America Protein Degradation Therapy Revenue Market Share by Type (2018-2033)
Figure 18. Europe Protein Degradation Therapy Revenue Market Share by Type (2018-2033)
Figure 19. Asia-Pacific Protein Degradation Therapy Revenue Market Share by Type (2018-2033)
Figure 20. Latin America Protein Degradation Therapy Revenue Market Share by Type (2018-2033)
Figure 21. Middle East and Africa Protein Degradation Therapy Revenue Market Share by Type (2018-2033)
Figure 22. Cancer Market Size (US$ Million) & YoY Growth (2018-2033)
Figure 23. Neuroscience Market Size (US$ Million) & YoY Growth (2018-2033)
Figure 24. Other Market Size (US$ Million) & YoY Growth (2018-2033)
Figure 25. Global Protein Degradation Therapy Market Size Share by Application: 2022 & 2033
Figure 26. North America Protein Degradation Therapy Revenue Market Share by Application (2018-2033)
Figure 27. Europe Protein Degradation Therapy Revenue Market Share by Application (2018-2033)
Figure 28. Asia-Pacific Protein Degradation Therapy Revenue Market Share by Application (2018-2033)
Figure 29. Latin America Protein Degradation Therapy Revenue Market Share by Application (2018-2033)
Figure 30. Middle East and Africa Protein Degradation Therapy Revenue Market Share by Application (2018-2033)
Figure 31. Protein Degradation Therapy Market Share by Company Type (Tier 1, Tier 2 and Tier 3): 2018 VS 2022
Figure 32. Global Top 5 and Top 10 Players Protein Degradation Therapy Market Share in 2022
Figure 33. North America Protein Degradation Therapy Market Share by Country (2018-2033)
Figure 34. United States Protein Degradation Therapy Market Size (2018-2033) & (US$ Million)
Figure 35. Canada Protein Degradation Therapy Market Size (2018-2033) & (US$ Million)
Figure 36. Germany Protein Degradation Therapy Market Size (2018-2033) & (US$ Million)
Figure 37. France Protein Degradation Therapy Market Size (2018-2033) & (US$ Million)
Figure 38. U.K. Protein Degradation Therapy Market Size (2018-2033) & (US$ Million)
Figure 39. Italy Protein Degradation Therapy Market Size (2018-2033) & (US$ Million)
Figure 40. Russia Protein Degradation Therapy Market Size (2018-2033) & (US$ Million)
Figure 41. Nordic Countries Protein Degradation Therapy Market Size (2018-2033) & (US$ Million)
Figure 42. Asia-Pacific Protein Degradation Therapy Market Share by Region (2018-2033)
Figure 43. China Protein Degradation Therapy Market Size (2018-2033) & (US$ Million)
Figure 44. Japan Protein Degradation Therapy Market Size (2018-2033) & (US$ Million)
Figure 45. South Korea Protein Degradation Therapy Market Size (2018-2033) & (US$ Million)
Figure 46. Southeast Asia Protein Degradation Therapy Market Size (2018-2033) & (US$ Million)
Figure 47. India Protein Degradation Therapy Market Size (2018-2033) & (US$ Million)
Figure 48. Australia Protein Degradation Therapy Market Size (2018-2033) & (US$ Million)
Figure 49. Latin America Protein Degradation Therapy Market Share by Country (2018-2033)
Figure 50. Mexico Protein Degradation Therapy Market Size (2018-2033) & (US$ Million)
Figure 51. Brazil Protein Degradation Therapy Market Size (2018-2033) & (US$ Million)
Figure 52. Middle East & Africa Protein Degradation Therapy Market Share by Country (2018-2033)
Figure 53. Turkey Protein Degradation Therapy Market Size (2018-2033) & (US$ Million)
Figure 54. Saudi Arabia Protein Degradation Therapy Market Size (2018-2033) & (US$ Million)
Figure 55. UAE Protein Degradation Therapy Market Size (2018-2033) & (US$ Million)
Figure 56. Bottom-up and Top-down Approaches for This Report

Global Protein Degradation Therapy Market Report, History and Forecast 2018-2034, Breakdown Data by Companies, Key Regions, Types and Application

Global Protein Degradation Therapy Market Report, History and Forecast 2018-2034, Breakdown Data by Companies, Key Regions, Types and Application

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