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Global Targeted-protein Degradation Therapeutics Market Research Report 2024

Published on: 2024-01-04 | No of Pages : 400 | Industry : Medical

Publisher : MRA | Format : PDF

Global Targeted-protein Degradation Therapeutics Market Research Report 2024

Targeted protein degradation (TPD) has surfaced as a novel and innovative chemical tool and therapeutic modality. By co-opting protein degradation pathways, TPD facilitates complete removal of the protein molecules from within or outside the cell. While the pioneering Proteolysis-Targeting Chimera (PROTAC) technology and molecular glues hijack the ubiquitin-proteasome system, newer modalities co-opt autophagy or the endo-lysosomal pathway.
According to MRAResearch’s new survey, global Targeted-protein Degradation Therapeutics market is projected to reach US$ 1821.4 million in 2033, increasing from US$ 1132 million in 2022, with the CAGR of 6.3% during the period of 2023 to 2033. Influencing issues, such as economy environments, COVID-19 and Russia-Ukraine War, have led to great market fluctuations in the past few years and are considered comprehensively in the whole Targeted-protein Degradation Therapeutics market research.
The Protein Degradation Therapy market has gained momentum as a promising approach in drug development. This innovative strategy aims to target disease-causing proteins by facilitating their degradation within cells. Proteins that contribute to diseases like cancer and neurodegenerative disorders can be selectively broken down using small molecules known as proteolysis-targeting chimeras (PROTACs) or other protein degraders. This approach offers advantages over traditional inhibition methods, potentially leading to more effective treatments with reduced side effects. As researchers delve into protein-protein interactions and cellular mechanisms, the Protein Degradation Therapy market is expanding, presenting opportunities to address previously challenging diseases and advance precision medicine. Clinical progress and continued research in this field are expected to shape the future of therapeutic interventions.
Report Scope
This report, based on historical analysis (2018-2022) and forecast calculation (2023-2033), aims to help readers to get a comprehensive understanding of global Targeted-protein Degradation Therapeutics market with multiple angles, which provides sufficient supports to readers’ strategy and decision making.



By Company


Arvinas
Nurix Therapeutics
Kymera Therapeutics
C4 Therapeutics
Segment by Type
ARV-110
ARV-471
Other

Segment by Application


Cancer
Neuroscience
Other
By Region
North America
United States
Canada
Europe
Germany
France
UK
Italy
Russia
Nordic Countries
Rest of Europe
Asia-Pacific
China
Japan
South Korea
Southeast Asia
India
Australia
Rest of Asia
Latin America
Mexico
Brazil
Rest of Latin America
Middle East & Africa
Turkey
Saudi Arabia
UAE
Rest of MEA
The Targeted-protein Degradation Therapeutics report covers below items
Chapter 1Product Basic Information (Definition, Type and Application)
Chapter 2Global market size, regional market size. Market Opportunities and Challenges
Chapter 3Companies’ Competition Patterns
Chapter 4Product Type Analysis
Chapter 5Product Application Analysis
Chapter 6 to 10Country Level Value Analysis
Chapter 11Companies' Outline
Chapter 12Market Conclusions
Chapter 13Research Methodology and Data Source

Table of Content

1 Report Overview
1.1 Study Scope
1.2 Market Analysis by Type
1.2.1 Global Targeted-protein Degradation Therapeutics Market Size Growth Rate by Type: 2018 VS 2022 VS 2033
1.2.2 ARV-110
1.2.3 ARV-471
1.2.4 Other
1.3 Market by Application
1.3.1 Global Targeted-protein Degradation Therapeutics Market Growth by Application: 2018 VS 2022 VS 2033
1.3.2 Cancer
1.3.3 Neuroscience
1.3.4 Other
1.4 Study Objectives
1.5 Years Considered
1.6 Years Considered
2 Global Growth Trends
2.1 Global Targeted-protein Degradation Therapeutics Market Perspective (2018-2033)
2.2 Targeted-protein Degradation Therapeutics Growth Trends by Region
2.2.1 Global Targeted-protein Degradation Therapeutics Market Size by Region: 2018 VS 2022 VS 2033
2.2.2 Targeted-protein Degradation Therapeutics Historic Market Size by Region (2018-2023)
2.2.3 Targeted-protein Degradation Therapeutics Forecasted Market Size by Region (2024-2033)
2.3 Targeted-protein Degradation Therapeutics Market Dynamics
2.3.1 Targeted-protein Degradation Therapeutics Industry Trends
2.3.2 Targeted-protein Degradation Therapeutics Market Drivers
2.3.3 Targeted-protein Degradation Therapeutics Market Challenges
2.3.4 Targeted-protein Degradation Therapeutics Market Restraints
3 Competition Landscape by Key Players
3.1 Global Top Targeted-protein Degradation Therapeutics Players by Revenue
3.1.1 Global Top Targeted-protein Degradation Therapeutics Players by Revenue (2018-2023)
3.1.2 Global Targeted-protein Degradation Therapeutics Revenue Market Share by Players (2018-2023)
3.2 Global Targeted-protein Degradation Therapeutics Market Share by Company Type (Tier 1, Tier 2, and Tier 3)
3.3 Players Covered: Ranking by Targeted-protein Degradation Therapeutics Revenue
3.4 Global Targeted-protein Degradation Therapeutics Market Concentration Ratio
3.4.1 Global Targeted-protein Degradation Therapeutics Market Concentration Ratio (CR5 and HHI)
3.4.2 Global Top 10 and Top 5 Companies by Targeted-protein Degradation Therapeutics Revenue in 2022
3.5 Targeted-protein Degradation Therapeutics Key Players Head office and Area Served
3.6 Key Players Targeted-protein Degradation Therapeutics Product Solution and Service
3.7 Date of Enter into Targeted-protein Degradation Therapeutics Market
3.8 Mergers & Acquisitions, Expansion Plans
4 Targeted-protein Degradation Therapeutics Breakdown Data by Type
4.1 Global Targeted-protein Degradation Therapeutics Historic Market Size by Type (2018-2023)
4.2 Global Targeted-protein Degradation Therapeutics Forecasted Market Size by Type (2024-2033)
5 Targeted-protein Degradation Therapeutics Breakdown Data by Application
5.1 Global Targeted-protein Degradation Therapeutics Historic Market Size by Application (2018-2023)
5.2 Global Targeted-protein Degradation Therapeutics Forecasted Market Size by Application (2024-2033)
6 North America
6.1 North America Targeted-protein Degradation Therapeutics Market Size (2018-2033)
6.2 North America Targeted-protein Degradation Therapeutics Market Growth Rate by Country: 2018 VS 2022 VS 2033
6.3 North America Targeted-protein Degradation Therapeutics Market Size by Country (2018-2023)
6.4 North America Targeted-protein Degradation Therapeutics Market Size by Country (2024-2033)
6.5 United States
6.6 Canada
7 Europe
7.1 Europe Targeted-protein Degradation Therapeutics Market Size (2018-2033)
7.2 Europe Targeted-protein Degradation Therapeutics Market Growth Rate by Country: 2018 VS 2022 VS 2033
7.3 Europe Targeted-protein Degradation Therapeutics Market Size by Country (2018-2023)
7.4 Europe Targeted-protein Degradation Therapeutics Market Size by Country (2024-2033)
7.5 Germany
7.6 France
7.7 U.K.
7.8 Italy
7.9 Russia
7.10 Nordic Countries
8 Asia-Pacific
8.1 Asia-Pacific Targeted-protein Degradation Therapeutics Market Size (2018-2033)
8.2 Asia-Pacific Targeted-protein Degradation Therapeutics Market Growth Rate by Region: 2018 VS 2022 VS 2033
8.3 Asia-Pacific Targeted-protein Degradation Therapeutics Market Size by Region (2018-2023)
8.4 Asia-Pacific Targeted-protein Degradation Therapeutics Market Size by Region (2024-2033)
8.5 China
8.6 Japan
8.7 South Korea
8.8 Southeast Asia
8.9 India
8.10 Australia
9 Latin America
9.1 Latin America Targeted-protein Degradation Therapeutics Market Size (2018-2033)
9.2 Latin America Targeted-protein Degradation Therapeutics Market Growth Rate by Country: 2018 VS 2022 VS 2033
9.3 Latin America Targeted-protein Degradation Therapeutics Market Size by Country (2018-2023)
9.4 Latin America Targeted-protein Degradation Therapeutics Market Size by Country (2024-2033)
9.5 Mexico
9.6 Brazil
10 Middle East & Africa
10.1 Middle East & Africa Targeted-protein Degradation Therapeutics Market Size (2018-2033)
10.2 Middle East & Africa Targeted-protein Degradation Therapeutics Market Growth Rate by Country: 2018 VS 2022 VS 2033
10.3 Middle East & Africa Targeted-protein Degradation Therapeutics Market Size by Country (2018-2023)
10.4 Middle East & Africa Targeted-protein Degradation Therapeutics Market Size by Country (2024-2033)
10.5 Turkey
10.6 Saudi Arabia
10.7 UAE
11 Key Players Profiles
11.1 Arvinas
11.1.1 Arvinas Company Detail
11.1.2 Arvinas Business Overview
11.1.3 Arvinas Targeted-protein Degradation Therapeutics Introduction
11.1.4 Arvinas Revenue in Targeted-protein Degradation Therapeutics Business (2018-2023)
11.1.5 Arvinas Recent Development
11.2 Nurix Therapeutics
11.2.1 Nurix Therapeutics Company Detail
11.2.2 Nurix Therapeutics Business Overview
11.2.3 Nurix Therapeutics Targeted-protein Degradation Therapeutics Introduction
11.2.4 Nurix Therapeutics Revenue in Targeted-protein Degradation Therapeutics Business (2018-2023)
11.2.5 Nurix Therapeutics Recent Development
11.3 Kymera Therapeutics
11.3.1 Kymera Therapeutics Company Detail
11.3.2 Kymera Therapeutics Business Overview
11.3.3 Kymera Therapeutics Targeted-protein Degradation Therapeutics Introduction
11.3.4 Kymera Therapeutics Revenue in Targeted-protein Degradation Therapeutics Business (2018-2023)
11.3.5 Kymera Therapeutics Recent Development
11.4 C4 Therapeutics
11.4.1 C4 Therapeutics Company Detail
11.4.2 C4 Therapeutics Business Overview
11.4.3 C4 Therapeutics Targeted-protein Degradation Therapeutics Introduction
11.4.4 C4 Therapeutics Revenue in Targeted-protein Degradation Therapeutics Business (2018-2023)
11.4.5 C4 Therapeutics Recent Development
12 Analyst's Viewpoints/Conclusions
13 Appendix
13.1 Research Methodology
13.1.1 Methodology/Research Approach
13.1.2 Data Source
13.2 Disclaimer
13.3 Author Details

List of Figure

List of Tables
Table 1. Global Targeted-protein Degradation Therapeutics Market Size Growth Rate by Type (US$ Million): 2018 VS 2022 VS 2033
Table 2. Key Players of ARV-110
Table 3. Key Players of ARV-471
Table 4. Key Players of Other
Table 5. Global Targeted-protein Degradation Therapeutics Market Size Growth by Application (US$ Million): 2018 VS 2022 VS 2033
Table 6. Global Targeted-protein Degradation Therapeutics Market Size by Region (US$ Million): 2018 VS 2022 VS 2033
Table 7. Global Targeted-protein Degradation Therapeutics Market Size by Region (2018-2023) & (US$ Million)
Table 8. Global Targeted-protein Degradation Therapeutics Market Share by Region (2018-2023)
Table 9. Global Targeted-protein Degradation Therapeutics Forecasted Market Size by Region (2024-2033) & (US$ Million)
Table 10. Global Targeted-protein Degradation Therapeutics Market Share by Region (2024-2033)
Table 11. Targeted-protein Degradation Therapeutics Market Trends
Table 12. Targeted-protein Degradation Therapeutics Market Drivers
Table 13. Targeted-protein Degradation Therapeutics Market Challenges
Table 14. Targeted-protein Degradation Therapeutics Market Restraints
Table 15. Global Targeted-protein Degradation Therapeutics Revenue by Players (2018-2023) & (US$ Million)
Table 16. Global Targeted-protein Degradation Therapeutics Market Share by Players (2018-2023)
Table 17. Global Top Targeted-protein Degradation Therapeutics Players by Company Type (Tier 1, Tier 2, and Tier 3) & (based on the Revenue in Targeted-protein Degradation Therapeutics as of 2022)
Table 18. Ranking of Global Top Targeted-protein Degradation Therapeutics Companies by Revenue (US$ Million) in 2022
Table 19. Global 5 Largest Players Market Share by Targeted-protein Degradation Therapeutics Revenue (CR5 and HHI) & (2018-2023)
Table 20. Key Players Headquarters and Area Served
Table 21. Key Players Targeted-protein Degradation Therapeutics Product Solution and Service
Table 22. Date of Enter into Targeted-protein Degradation Therapeutics Market
Table 23. Mergers & Acquisitions, Expansion Plans
Table 24. Global Targeted-protein Degradation Therapeutics Market Size by Type (2018-2023) & (US$ Million)
Table 25. Global Targeted-protein Degradation Therapeutics Revenue Market Share by Type (2018-2023)
Table 26. Global Targeted-protein Degradation Therapeutics Forecasted Market Size by Type (2024-2033) & (US$ Million)
Table 27. Global Targeted-protein Degradation Therapeutics Revenue Market Share by Type (2024-2033)
Table 28. Global Targeted-protein Degradation Therapeutics Market Size by Application (2018-2023) & (US$ Million)
Table 29. Global Targeted-protein Degradation Therapeutics Revenue Market Share by Application (2018-2023)
Table 30. Global Targeted-protein Degradation Therapeutics Forecasted Market Size by Application (2024-2033) & (US$ Million)
Table 31. Global Targeted-protein Degradation Therapeutics Revenue Market Share by Application (2024-2033)
Table 32. North America Targeted-protein Degradation Therapeutics Market Size Growth Rate by Country (US$ Million): 2018 VS 2022 VS 2033
Table 33. North America Targeted-protein Degradation Therapeutics Market Size by Country (2018-2023) & (US$ Million)
Table 34. North America Targeted-protein Degradation Therapeutics Market Size by Country (2024-2033) & (US$ Million)
Table 35. Europe Targeted-protein Degradation Therapeutics Market Size Growth Rate by Country (US$ Million): 2018 VS 2022 VS 2033
Table 36. Europe Targeted-protein Degradation Therapeutics Market Size by Country (2018-2023) & (US$ Million)
Table 37. Europe Targeted-protein Degradation Therapeutics Market Size by Country (2024-2033) & (US$ Million)
Table 38. Asia-Pacific Targeted-protein Degradation Therapeutics Market Size Growth Rate by Region (US$ Million): 2018 VS 2022 VS 2033
Table 39. Asia-Pacific Targeted-protein Degradation Therapeutics Market Size by Region (2018-2023) & (US$ Million)
Table 40. Asia-Pacific Targeted-protein Degradation Therapeutics Market Size by Region (2024-2033) & (US$ Million)
Table 41. Latin America Targeted-protein Degradation Therapeutics Market Size Growth Rate by Country (US$ Million): 2018 VS 2022 VS 2033
Table 42. Latin America Targeted-protein Degradation Therapeutics Market Size by Country (2018-2023) & (US$ Million)
Table 43. Latin America Targeted-protein Degradation Therapeutics Market Size by Country (2024-2033) & (US$ Million)
Table 44. Middle East & Africa Targeted-protein Degradation Therapeutics Market Size Growth Rate by Country (US$ Million): 2018 VS 2022 VS 2033
Table 45. Middle East & Africa Targeted-protein Degradation Therapeutics Market Size by Country (2018-2023) & (US$ Million)
Table 46. Middle East & Africa Targeted-protein Degradation Therapeutics Market Size by Country (2024-2033) & (US$ Million)
Table 47. Arvinas Company Detail
Table 48. Arvinas Business Overview
Table 49. Arvinas Targeted-protein Degradation Therapeutics Product
Table 50. Arvinas Revenue in Targeted-protein Degradation Therapeutics Business (2018-2023) & (US$ Million)
Table 51. Arvinas Recent Development
Table 52. Nurix Therapeutics Company Detail
Table 53. Nurix Therapeutics Business Overview
Table 54. Nurix Therapeutics Targeted-protein Degradation Therapeutics Product
Table 55. Nurix Therapeutics Revenue in Targeted-protein Degradation Therapeutics Business (2018-2023) & (US$ Million)
Table 56. Nurix Therapeutics Recent Development
Table 57. Kymera Therapeutics Company Detail
Table 58. Kymera Therapeutics Business Overview
Table 59. Kymera Therapeutics Targeted-protein Degradation Therapeutics Product
Table 60. Kymera Therapeutics Revenue in Targeted-protein Degradation Therapeutics Business (2018-2023) & (US$ Million)
Table 61. Kymera Therapeutics Recent Development
Table 62. C4 Therapeutics Company Detail
Table 63. C4 Therapeutics Business Overview
Table 64. C4 Therapeutics Targeted-protein Degradation Therapeutics Product
Table 65. C4 Therapeutics Revenue in Targeted-protein Degradation Therapeutics Business (2018-2023) & (US$ Million)
Table 66. C4 Therapeutics Recent Development
Table 67. Research Programs/Design for This Report
Table 68. Key Data Information from Secondary Sources
Table 69. Key Data Information from Primary Sources
List of Figures
Figure 1. Global Targeted-protein Degradation Therapeutics Market Size Comparison by Type (2023-2033) & (US$ Million)
Figure 2. Global Targeted-protein Degradation Therapeutics Market Share by Type: 2022 VS 2033
Figure 3. ARV-110 Features
Figure 4. ARV-471 Features
Figure 5. Other Features
Figure 6. Global Targeted-protein Degradation Therapeutics Market Size Comparison by Application (2023-2033) & (US$ Million)
Figure 7. Global Targeted-protein Degradation Therapeutics Market Share by Application: 2022 VS 2033
Figure 8. Cancer Case Studies
Figure 9. Neuroscience Case Studies
Figure 10. Other Case Studies
Figure 11. Targeted-protein Degradation Therapeutics Report Years Considered
Figure 12. Global Targeted-protein Degradation Therapeutics Market Size (US$ Million), Year-over-Year: 2018-2033
Figure 13. Global Targeted-protein Degradation Therapeutics Market Size, (US$ Million), 2018 VS 2022 VS 2033
Figure 14. Global Targeted-protein Degradation Therapeutics Market Share by Region: 2022 VS 2033
Figure 15. Global Targeted-protein Degradation Therapeutics Market Share by Players in 2022
Figure 16. Global Top Targeted-protein Degradation Therapeutics Players by Company Type (Tier 1, Tier 2, and Tier 3) & (based on the Revenue in Targeted-protein Degradation Therapeutics as of 2022)
Figure 17. The Top 10 and 5 Players Market Share by Targeted-protein Degradation Therapeutics Revenue in 2022
Figure 18. North America Targeted-protein Degradation Therapeutics Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 19. North America Targeted-protein Degradation Therapeutics Market Share by Country (2018-2033)
Figure 20. United States Targeted-protein Degradation Therapeutics Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 21. Canada Targeted-protein Degradation Therapeutics Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 22. Europe Targeted-protein Degradation Therapeutics Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 23. Europe Targeted-protein Degradation Therapeutics Market Share by Country (2018-2033)
Figure 24. Germany Targeted-protein Degradation Therapeutics Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 25. France Targeted-protein Degradation Therapeutics Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 26. U.K. Targeted-protein Degradation Therapeutics Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 27. Italy Targeted-protein Degradation Therapeutics Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 28. Russia Targeted-protein Degradation Therapeutics Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 29. Nordic Countries Targeted-protein Degradation Therapeutics Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 30. Asia-Pacific Targeted-protein Degradation Therapeutics Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 31. Asia-Pacific Targeted-protein Degradation Therapeutics Market Share by Region (2018-2033)
Figure 32. China Targeted-protein Degradation Therapeutics Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 33. Japan Targeted-protein Degradation Therapeutics Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 34. South Korea Targeted-protein Degradation Therapeutics Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 35. Southeast Asia Targeted-protein Degradation Therapeutics Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 36. India Targeted-protein Degradation Therapeutics Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 37. Australia Targeted-protein Degradation Therapeutics Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 38. Latin America Targeted-protein Degradation Therapeutics Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 39. Latin America Targeted-protein Degradation Therapeutics Market Share by Country (2018-2033)
Figure 40. Mexico Targeted-protein Degradation Therapeutics Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 41. Brazil Targeted-protein Degradation Therapeutics Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 42. Middle East & Africa Targeted-protein Degradation Therapeutics Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 43. Middle East & Africa Targeted-protein Degradation Therapeutics Market Share by Country (2018-2033)
Figure 44. Turkey Targeted-protein Degradation Therapeutics Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 45. Saudi Arabia Targeted-protein Degradation Therapeutics Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 46. Arvinas Revenue Growth Rate in Targeted-protein Degradation Therapeutics Business (2018-2023)
Figure 47. Nurix Therapeutics Revenue Growth Rate in Targeted-protein Degradation Therapeutics Business (2018-2023)
Figure 48. Kymera Therapeutics Revenue Growth Rate in Targeted-protein Degradation Therapeutics Business (2018-2023)
Figure 49. C4 Therapeutics Revenue Growth Rate in Targeted-protein Degradation Therapeutics Business (2018-2023)
Figure 50. Bottom-up and Top-down Approaches for This Report
Figure 51. Data Triangulation
Figure 52. Key Executives Interviewed

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