img

Global Protein Degradation Therapy Market Research Report 2024


Published on: 2024-01-04 | No of Pages : 400 | Industry : Medical

Publisher : MRA | Format : PDF

Global Protein Degradation Therapy Market Research Report 2024

Targeted protein degradation (TPD) has surfaced as a novel and innovative chemical tool and therapeutic modality. By co-opting protein degradation pathways, TPD facilitates complete removal of the protein molecules from within or outside the cell. While the pioneering Proteolysis-Targeting Chimera (PROTAC) technology and molecular glues hijack the ubiquitin-proteasome system, newer modalities co-opt autophagy or the endo-lysosomal pathway.
According to MRAResearch’s new survey, global Protein Degradation Therapy market is projected to reach US$ 1821.4 million in 2033, increasing from US$ 1132 million in 2022, with the CAGR of 6.3% during the period of 2023 to 2033. Influencing issues, such as economy environments, COVID-19 and Russia-Ukraine War, have led to great market fluctuations in the past few years and are considered comprehensively in the whole Protein Degradation Therapy market research.
The Protein Degradation Therapy market has gained momentum as a promising approach in drug development. This innovative strategy aims to target disease-causing proteins by facilitating their degradation within cells. Proteins that contribute to diseases like cancer and neurodegenerative disorders can be selectively broken down using small molecules known as proteolysis-targeting chimeras (PROTACs) or other protein degraders. This approach offers advantages over traditional inhibition methods, potentially leading to more effective treatments with reduced side effects. As researchers delve into protein-protein interactions and cellular mechanisms, the Protein Degradation Therapy market is expanding, presenting opportunities to address previously challenging diseases and advance precision medicine. Clinical progress and continued research in this field are expected to shape the future of therapeutic interventions.
Report Scope
This report, based on historical analysis (2018-2022) and forecast calculation (2023-2033), aims to help readers to get a comprehensive understanding of global Protein Degradation Therapy market with multiple angles, which provides sufficient supports to readers’ strategy and decision making.



By Company


Arvinas
Nurix Therapeutics
Kymera Therapeutics
C4 Therapeutics
Segment by Type
ARV-110
ARV-471
Other

Segment by Application


Cancer
Neuroscience
Other
By Region
North America
United States
Canada
Europe
Germany
France
UK
Italy
Russia
Nordic Countries
Rest of Europe
Asia-Pacific
China
Japan
South Korea
Southeast Asia
India
Australia
Rest of Asia
Latin America
Mexico
Brazil
Rest of Latin America
Middle East & Africa
Turkey
Saudi Arabia
UAE
Rest of MEA
The Protein Degradation Therapy report covers below items
Chapter 1Product Basic Information (Definition, Type and Application)
Chapter 2Global market size, regional market size. Market Opportunities and Challenges
Chapter 3Companies’ Competition Patterns
Chapter 4Product Type Analysis
Chapter 5Product Application Analysis
Chapter 6 to 10Country Level Value Analysis
Chapter 11Companies' Outline
Chapter 12Market Conclusions
Chapter 13Research Methodology and Data Source

Table of Content

1 Report Overview
1.1 Study Scope
1.2 Market Analysis by Type
1.2.1 Global Protein Degradation Therapy Market Size Growth Rate by Type: 2018 VS 2022 VS 2033
1.2.2 ARV-110
1.2.3 ARV-471
1.2.4 Other
1.3 Market by Application
1.3.1 Global Protein Degradation Therapy Market Growth by Application: 2018 VS 2022 VS 2033
1.3.2 Cancer
1.3.3 Neuroscience
1.3.4 Other
1.4 Study Objectives
1.5 Years Considered
1.6 Years Considered
2 Global Growth Trends
2.1 Global Protein Degradation Therapy Market Perspective (2018-2033)
2.2 Protein Degradation Therapy Growth Trends by Region
2.2.1 Global Protein Degradation Therapy Market Size by Region: 2018 VS 2022 VS 2033
2.2.2 Protein Degradation Therapy Historic Market Size by Region (2018-2023)
2.2.3 Protein Degradation Therapy Forecasted Market Size by Region (2024-2033)
2.3 Protein Degradation Therapy Market Dynamics
2.3.1 Protein Degradation Therapy Industry Trends
2.3.2 Protein Degradation Therapy Market Drivers
2.3.3 Protein Degradation Therapy Market Challenges
2.3.4 Protein Degradation Therapy Market Restraints
3 Competition Landscape by Key Players
3.1 Global Top Protein Degradation Therapy Players by Revenue
3.1.1 Global Top Protein Degradation Therapy Players by Revenue (2018-2023)
3.1.2 Global Protein Degradation Therapy Revenue Market Share by Players (2018-2023)
3.2 Global Protein Degradation Therapy Market Share by Company Type (Tier 1, Tier 2, and Tier 3)
3.3 Players Covered: Ranking by Protein Degradation Therapy Revenue
3.4 Global Protein Degradation Therapy Market Concentration Ratio
3.4.1 Global Protein Degradation Therapy Market Concentration Ratio (CR5 and HHI)
3.4.2 Global Top 10 and Top 5 Companies by Protein Degradation Therapy Revenue in 2022
3.5 Protein Degradation Therapy Key Players Head office and Area Served
3.6 Key Players Protein Degradation Therapy Product Solution and Service
3.7 Date of Enter into Protein Degradation Therapy Market
3.8 Mergers & Acquisitions, Expansion Plans
4 Protein Degradation Therapy Breakdown Data by Type
4.1 Global Protein Degradation Therapy Historic Market Size by Type (2018-2023)
4.2 Global Protein Degradation Therapy Forecasted Market Size by Type (2024-2033)
5 Protein Degradation Therapy Breakdown Data by Application
5.1 Global Protein Degradation Therapy Historic Market Size by Application (2018-2023)
5.2 Global Protein Degradation Therapy Forecasted Market Size by Application (2024-2033)
6 North America
6.1 North America Protein Degradation Therapy Market Size (2018-2033)
6.2 North America Protein Degradation Therapy Market Growth Rate by Country: 2018 VS 2022 VS 2033
6.3 North America Protein Degradation Therapy Market Size by Country (2018-2023)
6.4 North America Protein Degradation Therapy Market Size by Country (2024-2033)
6.5 United States
6.6 Canada
7 Europe
7.1 Europe Protein Degradation Therapy Market Size (2018-2033)
7.2 Europe Protein Degradation Therapy Market Growth Rate by Country: 2018 VS 2022 VS 2033
7.3 Europe Protein Degradation Therapy Market Size by Country (2018-2023)
7.4 Europe Protein Degradation Therapy Market Size by Country (2024-2033)
7.5 Germany
7.6 France
7.7 U.K.
7.8 Italy
7.9 Russia
7.10 Nordic Countries
8 Asia-Pacific
8.1 Asia-Pacific Protein Degradation Therapy Market Size (2018-2033)
8.2 Asia-Pacific Protein Degradation Therapy Market Growth Rate by Region: 2018 VS 2022 VS 2033
8.3 Asia-Pacific Protein Degradation Therapy Market Size by Region (2018-2023)
8.4 Asia-Pacific Protein Degradation Therapy Market Size by Region (2024-2033)
8.5 China
8.6 Japan
8.7 South Korea
8.8 Southeast Asia
8.9 India
8.10 Australia
9 Latin America
9.1 Latin America Protein Degradation Therapy Market Size (2018-2033)
9.2 Latin America Protein Degradation Therapy Market Growth Rate by Country: 2018 VS 2022 VS 2033
9.3 Latin America Protein Degradation Therapy Market Size by Country (2018-2023)
9.4 Latin America Protein Degradation Therapy Market Size by Country (2024-2033)
9.5 Mexico
9.6 Brazil
10 Middle East & Africa
10.1 Middle East & Africa Protein Degradation Therapy Market Size (2018-2033)
10.2 Middle East & Africa Protein Degradation Therapy Market Growth Rate by Country: 2018 VS 2022 VS 2033
10.3 Middle East & Africa Protein Degradation Therapy Market Size by Country (2018-2023)
10.4 Middle East & Africa Protein Degradation Therapy Market Size by Country (2024-2033)
10.5 Turkey
10.6 Saudi Arabia
10.7 UAE
11 Key Players Profiles
11.1 Arvinas
11.1.1 Arvinas Company Detail
11.1.2 Arvinas Business Overview
11.1.3 Arvinas Protein Degradation Therapy Introduction
11.1.4 Arvinas Revenue in Protein Degradation Therapy Business (2018-2023)
11.1.5 Arvinas Recent Development
11.2 Nurix Therapeutics
11.2.1 Nurix Therapeutics Company Detail
11.2.2 Nurix Therapeutics Business Overview
11.2.3 Nurix Therapeutics Protein Degradation Therapy Introduction
11.2.4 Nurix Therapeutics Revenue in Protein Degradation Therapy Business (2018-2023)
11.2.5 Nurix Therapeutics Recent Development
11.3 Kymera Therapeutics
11.3.1 Kymera Therapeutics Company Detail
11.3.2 Kymera Therapeutics Business Overview
11.3.3 Kymera Therapeutics Protein Degradation Therapy Introduction
11.3.4 Kymera Therapeutics Revenue in Protein Degradation Therapy Business (2018-2023)
11.3.5 Kymera Therapeutics Recent Development
11.4 C4 Therapeutics
11.4.1 C4 Therapeutics Company Detail
11.4.2 C4 Therapeutics Business Overview
11.4.3 C4 Therapeutics Protein Degradation Therapy Introduction
11.4.4 C4 Therapeutics Revenue in Protein Degradation Therapy Business (2018-2023)
11.4.5 C4 Therapeutics Recent Development
12 Analyst's Viewpoints/Conclusions
13 Appendix
13.1 Research Methodology
13.1.1 Methodology/Research Approach
13.1.2 Data Source
13.2 Disclaimer
13.3 Author Details

List of Figure

List of Tables
Table 1. Global Protein Degradation Therapy Market Size Growth Rate by Type (US$ Million): 2018 VS 2022 VS 2033
Table 2. Key Players of ARV-110
Table 3. Key Players of ARV-471
Table 4. Key Players of Other
Table 5. Global Protein Degradation Therapy Market Size Growth by Application (US$ Million): 2018 VS 2022 VS 2033
Table 6. Global Protein Degradation Therapy Market Size by Region (US$ Million): 2018 VS 2022 VS 2033
Table 7. Global Protein Degradation Therapy Market Size by Region (2018-2023) & (US$ Million)
Table 8. Global Protein Degradation Therapy Market Share by Region (2018-2023)
Table 9. Global Protein Degradation Therapy Forecasted Market Size by Region (2024-2033) & (US$ Million)
Table 10. Global Protein Degradation Therapy Market Share by Region (2024-2033)
Table 11. Protein Degradation Therapy Market Trends
Table 12. Protein Degradation Therapy Market Drivers
Table 13. Protein Degradation Therapy Market Challenges
Table 14. Protein Degradation Therapy Market Restraints
Table 15. Global Protein Degradation Therapy Revenue by Players (2018-2023) & (US$ Million)
Table 16. Global Protein Degradation Therapy Market Share by Players (2018-2023)
Table 17. Global Top Protein Degradation Therapy Players by Company Type (Tier 1, Tier 2, and Tier 3) & (based on the Revenue in Protein Degradation Therapy as of 2022)
Table 18. Ranking of Global Top Protein Degradation Therapy Companies by Revenue (US$ Million) in 2022
Table 19. Global 5 Largest Players Market Share by Protein Degradation Therapy Revenue (CR5 and HHI) & (2018-2023)
Table 20. Key Players Headquarters and Area Served
Table 21. Key Players Protein Degradation Therapy Product Solution and Service
Table 22. Date of Enter into Protein Degradation Therapy Market
Table 23. Mergers & Acquisitions, Expansion Plans
Table 24. Global Protein Degradation Therapy Market Size by Type (2018-2023) & (US$ Million)
Table 25. Global Protein Degradation Therapy Revenue Market Share by Type (2018-2023)
Table 26. Global Protein Degradation Therapy Forecasted Market Size by Type (2024-2033) & (US$ Million)
Table 27. Global Protein Degradation Therapy Revenue Market Share by Type (2024-2033)
Table 28. Global Protein Degradation Therapy Market Size by Application (2018-2023) & (US$ Million)
Table 29. Global Protein Degradation Therapy Revenue Market Share by Application (2018-2023)
Table 30. Global Protein Degradation Therapy Forecasted Market Size by Application (2024-2033) & (US$ Million)
Table 31. Global Protein Degradation Therapy Revenue Market Share by Application (2024-2033)
Table 32. North America Protein Degradation Therapy Market Size Growth Rate by Country (US$ Million): 2018 VS 2022 VS 2033
Table 33. North America Protein Degradation Therapy Market Size by Country (2018-2023) & (US$ Million)
Table 34. North America Protein Degradation Therapy Market Size by Country (2024-2033) & (US$ Million)
Table 35. Europe Protein Degradation Therapy Market Size Growth Rate by Country (US$ Million): 2018 VS 2022 VS 2033
Table 36. Europe Protein Degradation Therapy Market Size by Country (2018-2023) & (US$ Million)
Table 37. Europe Protein Degradation Therapy Market Size by Country (2024-2033) & (US$ Million)
Table 38. Asia-Pacific Protein Degradation Therapy Market Size Growth Rate by Region (US$ Million): 2018 VS 2022 VS 2033
Table 39. Asia-Pacific Protein Degradation Therapy Market Size by Region (2018-2023) & (US$ Million)
Table 40. Asia-Pacific Protein Degradation Therapy Market Size by Region (2024-2033) & (US$ Million)
Table 41. Latin America Protein Degradation Therapy Market Size Growth Rate by Country (US$ Million): 2018 VS 2022 VS 2033
Table 42. Latin America Protein Degradation Therapy Market Size by Country (2018-2023) & (US$ Million)
Table 43. Latin America Protein Degradation Therapy Market Size by Country (2024-2033) & (US$ Million)
Table 44. Middle East & Africa Protein Degradation Therapy Market Size Growth Rate by Country (US$ Million): 2018 VS 2022 VS 2033
Table 45. Middle East & Africa Protein Degradation Therapy Market Size by Country (2018-2023) & (US$ Million)
Table 46. Middle East & Africa Protein Degradation Therapy Market Size by Country (2024-2033) & (US$ Million)
Table 47. Arvinas Company Detail
Table 48. Arvinas Business Overview
Table 49. Arvinas Protein Degradation Therapy Product
Table 50. Arvinas Revenue in Protein Degradation Therapy Business (2018-2023) & (US$ Million)
Table 51. Arvinas Recent Development
Table 52. Nurix Therapeutics Company Detail
Table 53. Nurix Therapeutics Business Overview
Table 54. Nurix Therapeutics Protein Degradation Therapy Product
Table 55. Nurix Therapeutics Revenue in Protein Degradation Therapy Business (2018-2023) & (US$ Million)
Table 56. Nurix Therapeutics Recent Development
Table 57. Kymera Therapeutics Company Detail
Table 58. Kymera Therapeutics Business Overview
Table 59. Kymera Therapeutics Protein Degradation Therapy Product
Table 60. Kymera Therapeutics Revenue in Protein Degradation Therapy Business (2018-2023) & (US$ Million)
Table 61. Kymera Therapeutics Recent Development
Table 62. C4 Therapeutics Company Detail
Table 63. C4 Therapeutics Business Overview
Table 64. C4 Therapeutics Protein Degradation Therapy Product
Table 65. C4 Therapeutics Revenue in Protein Degradation Therapy Business (2018-2023) & (US$ Million)
Table 66. C4 Therapeutics Recent Development
Table 67. Research Programs/Design for This Report
Table 68. Key Data Information from Secondary Sources
Table 69. Key Data Information from Primary Sources
List of Figures
Figure 1. Global Protein Degradation Therapy Market Size Comparison by Type (2023-2033) & (US$ Million)
Figure 2. Global Protein Degradation Therapy Market Share by Type: 2022 VS 2033
Figure 3. ARV-110 Features
Figure 4. ARV-471 Features
Figure 5. Other Features
Figure 6. Global Protein Degradation Therapy Market Size Comparison by Application (2023-2033) & (US$ Million)
Figure 7. Global Protein Degradation Therapy Market Share by Application: 2022 VS 2033
Figure 8. Cancer Case Studies
Figure 9. Neuroscience Case Studies
Figure 10. Other Case Studies
Figure 11. Protein Degradation Therapy Report Years Considered
Figure 12. Global Protein Degradation Therapy Market Size (US$ Million), Year-over-Year: 2018-2033
Figure 13. Global Protein Degradation Therapy Market Size, (US$ Million), 2018 VS 2022 VS 2033
Figure 14. Global Protein Degradation Therapy Market Share by Region: 2022 VS 2033
Figure 15. Global Protein Degradation Therapy Market Share by Players in 2022
Figure 16. Global Top Protein Degradation Therapy Players by Company Type (Tier 1, Tier 2, and Tier 3) & (based on the Revenue in Protein Degradation Therapy as of 2022)
Figure 17. The Top 10 and 5 Players Market Share by Protein Degradation Therapy Revenue in 2022
Figure 18. North America Protein Degradation Therapy Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 19. North America Protein Degradation Therapy Market Share by Country (2018-2033)
Figure 20. United States Protein Degradation Therapy Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 21. Canada Protein Degradation Therapy Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 22. Europe Protein Degradation Therapy Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 23. Europe Protein Degradation Therapy Market Share by Country (2018-2033)
Figure 24. Germany Protein Degradation Therapy Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 25. France Protein Degradation Therapy Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 26. U.K. Protein Degradation Therapy Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 27. Italy Protein Degradation Therapy Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 28. Russia Protein Degradation Therapy Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 29. Nordic Countries Protein Degradation Therapy Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 30. Asia-Pacific Protein Degradation Therapy Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 31. Asia-Pacific Protein Degradation Therapy Market Share by Region (2018-2033)
Figure 32. China Protein Degradation Therapy Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 33. Japan Protein Degradation Therapy Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 34. South Korea Protein Degradation Therapy Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 35. Southeast Asia Protein Degradation Therapy Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 36. India Protein Degradation Therapy Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 37. Australia Protein Degradation Therapy Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 38. Latin America Protein Degradation Therapy Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 39. Latin America Protein Degradation Therapy Market Share by Country (2018-2033)
Figure 40. Mexico Protein Degradation Therapy Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 41. Brazil Protein Degradation Therapy Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 42. Middle East & Africa Protein Degradation Therapy Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 43. Middle East & Africa Protein Degradation Therapy Market Share by Country (2018-2033)
Figure 44. Turkey Protein Degradation Therapy Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 45. Saudi Arabia Protein Degradation Therapy Market Size YoY Growth (2018-2033) & (US$ Million)
Figure 46. Arvinas Revenue Growth Rate in Protein Degradation Therapy Business (2018-2023)
Figure 47. Nurix Therapeutics Revenue Growth Rate in Protein Degradation Therapy Business (2018-2023)
Figure 48. Kymera Therapeutics Revenue Growth Rate in Protein Degradation Therapy Business (2018-2023)
Figure 49. C4 Therapeutics Revenue Growth Rate in Protein Degradation Therapy Business (2018-2023)
Figure 50. Bottom-up and Top-down Approaches for This Report
Figure 51. Data Triangulation
Figure 52. Key Executives Interviewed